NuLink Benzylic Azide
Azide Reagent, 15 angstrom Spacer, SKU NCAZ02
Safety and Documentation
NuLink Alkyl Azide
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) has been widely utilized in applications of bioconjugation. The CuAAC reaction involves the coupling of an azide and a terminal alkyne to form a stable triazole linkage between two disparate molecular entities. In addition to the CuAAC reaction, the catalyst free strain-promoted azide-alkyne cycloaddition (SPAAC) is emerging as a dominant method for bioconjugation. Unlike the CuAAC reaction where a terminal alkyne is requisite, SPAAC makes use of an internal cyclic alkyne with sufficient ring-strain to promote the cycloaddition with its cognate azide. While these coupling processes are straight forward neither azides nor alkynes occur naturally in biomolecules. NuChemie’s azide-alkyne reagent set is the simplest easy-to-use method for the incorporation and quantification of both azides and alkynes into almost any biomolecule platform.
Chemical Formula: C24H29IN6O4, Molecular Weight: 592.44
No Safety Information is available for this product at this time. This product is made available for research purposes only.
Protocols for the labeling of proteins, including antibodies (ABs) and carrier proteins have been provided in the documents below. Each document details reaction conditions, and includes information regarding buffer compatibility, reaction kinetics, and troubleshooting for the most commonly encountered problems.
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