Thiol incorporation, SKU NCT001
Safety and Documentation
The incorporation of thiols into proteins is commonly performed to allow for further conjugation via Michael addition, or disulfide formation. Similar to commercially available Traut's reagent, NuChemie's thiolation reagent is an amine reactive reagent for the introduction of a primary thiol. NuChemie's reagent introduces a constitutive quaternary ammonium salt enabling maintenance of charge properties of amines under physiological conditions. Like Traut's reagent, NuChemie's thiolation reagent is water-soluble, however, unlike Traut's reagent NuChemie's thiolation reagent is quantifiable and traceable using its inherent UV chromophore.
Chemical Formula: C24H29IN2O6S, Molecular Weight: 600.47
No Safety Information is available for this product at this time. This product is made available for research purposes only.
Protocols for the labeling of proteins, including antibodies (ABs) and carrier proteins have been provided in the documents below. Each document details reaction conditions, and includes information regarding buffer compatibility, reaction kinetics, and troubleshooting for the most commonly encountered problems.
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