NuChemie’s proprietary NuLink technology is a state-of-the-art bioconjugation platform offering the simplest, most reliable means of generating routine bioconjugates. NuLink reagents combine ease-of-use with the convenience of water-solubility to easily integrate with existing workflows. Additionally, each NuLink reagent enables direct quantification using NuLink’s unique spectral properties.
Quaternary ammonium salt aids
water solubility minimizing need for
Carbonyl reacts readily with amines yet is stable toward hydrolysis
NuLink reagents are each specifically engineered to install a particular chemical
CO2 is the only byproduct
of the Labeling Reaction
NuLink bioconjugates confer a unique absorbance and fluorescence to the biomolecule. This enables direct quantification with UV and enables low limits of detection using fluorescence.
Labeling of BSA with NCPD01 at pH 8.4
Degree of Labeling (DOL)
Bioconjugates with DOL < 4 can be ready in as little as 1 min.
Linker length removes functional group from the surface of the biomolecule enabling the desired chemistry to proceed uninhibited. Each nulink reagent has its own unique linker length and many reagents can be tailored to the desired purpose.
The linker is arguably the most important component of bioconjugates conferring a variety of both chemical and physical properties. NuLink offers reagents with a variety of linker lengths and compositions comprising one of the most complete bioconjugate platforms available. NuChemie NuLink "linkers" provide;
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